Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart
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چکیده
منابع مشابه
Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart
The clinical use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. The present study investigated the effects of scutellarin against DOX-induced cardiotoxicity in rats using pharmacodynamic and pharmacokinetic approaches. DOX (20 mg/kg) was injected intraperitoneally (i.p.) as a single dose, and scutellarin (5 mg/kg/day) was injected intravenously (i.v.) for 3 days. Rats tre...
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ژورنال
عنوان ژورنال: Archives of Pharmacal Research
سال: 2017
ISSN: 0253-6269,1976-3786
DOI: 10.1007/s12272-017-0907-0